To become sustainable, Europe must change some of the ways people live, work, produce and consume. Using policy to achieve such complex and large-scale transformations is not easy. This briefing explores how to future-proof sustainability policies and avoid blind spots through a foresight-based framework, which includes several participatory exercises involving a multidisciplinary group of experts. Assessing future risks and their potential impacts can identify mitigation measures and safeguard strategies to encourage the transition to sustainability and feed future policy.