US nuclear capacity has the potential to triple from ~100 GW in 2024 to ~300 GW by 2050. AI and data center load growth is aligning the fundamentals for new nuclear with requirements for 24/7 power, valuing decarbonization, and investment in new generation assets. In 2022, utilities were shutting down nuclear reactors; in 2024, they are extending reactor operations to 80 years, planning to uprate capacity, and restarting formerly closed reactors. Nuclear provides a differentiated value proposition for a decarbonized grid. Nuclear generates carbon-free electricity, provides firm power that complements renewables, has low land-use requirements, and has lower transmission requirements than distributed or site-constrained generation sources. It also offers high-paying jobs and significant regional economic benefits, can aid in an equitable transition to a net-zero grid, and has a wide variety of use cases that enable grid flexibility and decarbonization beyond the grid, including high temperatures for industrial heat.