Hydrogen is recognized as a pivotal element in the shift toward a low-carbon economy, presenting a clean energy alternative for sectors that are particularly challenging to decarbonize. Nevertheless, hydrogen’s efficacy as a sustainable solution faces constraints due to the potential environmental impacts linked to leakage across its supply chain – from production through to end-use. This paper offers a detailed review of hydrogen leakage rates, examines technological and regulatory measures aimed at minimizing leakage, and assesses the environmental implications of hydrogen release into the atmosphere. This paper explains why even minimal hydrogen leakage can exacerbate climate change by prolonging the atmospheric presence of methane and modifying ozone levels, thus producing indirect global warming effects. Addressing these issues necessitates a comprehensive approach encompassing investment in advanced containment materials, improved leak detection systems, retrofitting of existing infrastructure, and stringent regulatory standards.